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This means that serotonin is a chemical substance synthesized in the brain that performs a large number of activities in the central nervous system.
Serotonin structure. Serotonin is a chemical nerve cells produce. The structures of serotonin and related compounds are shown in figure 13 1. The findings provide insights for designing new ways to target the transporter for more effective medications. Structure properties spectra suppliers and links for.
As we have discussed serotonin is popularly known as a hormone that secretes the human body. More specifically however serotonin is a monoamine neurotransmitter ie a neurotransmitter. Serotonin s r e t o n n s er e or 5 hydroxytryptamine 5 ht is a monoamine neurotransmitterits biological function is complex and multifaceted modulating mood cognition reward learning memory and numerous physiological processes such as vomiting and vasoconstriction. The combination of the hydroxyl group in the 5 position of the indole nucleus and a primary amine nitrogen serving as a proton acceptor at physiological ph makes 5 hta hydrophilic substance.
As such it does not pass the lipophilic bloodbrain barrier readily. It is a monoamine molecular messenger a primary amino compound a member of phenols a member of hydroxyindoles and a member of tryptamines. Serotonin is a primary amino compound that is the 5 hydroxy derivative of tryptamineit has a role as a human metabolite a mouse metabolite and a neurotransmitter. It sends signals between your nerve cells.
But too much serotonin causes signs and symptoms that can range from mild shivering and diarrhea to severe muscle rigidity fever and seizures. Severe serotonin syndrome can cause death if not treated. Serotonin is a chemical your body produces thats needed for your nerve cells and brain to function. Serotonin hydrochloride c10h13cln2o cid 160436 structure chemical names physical and chemical properties classification patents literature biological.
Serotonin is found mostly in the digestive system although its also in blood platelets and throughout the. Slice through the human serotonin transporter structure illustrating the ssri binding sites.
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